刘昌胜 中国科学院院士

教育背景

1989年毕业于湖北大学生物学专业,获理学学士学位;

1992年毕业于华东理工大学生物化工专业,获工学硕士学位;

1996年毕业于华东理工大学化学工程专业,获工学博士学位。

工作履历

1992年至1993年在华东理工大学生化工程学科,任助教;

1993年至1999年在华东理工大学技物所,历任助教、讲师、副教授、教授,研究室主任、副所长、党支部书记。

1999年至2008年华东理工大学材料科学与工程学院生物材料研究所所长,教授,博士生导师。

2001年至今教育部医用生物材料工程研究中心主任,其中,2005年3月至9月,美国University of Pennsylvania访问教授。

2009年至今华东理工大学材料科学与工程学院院长。

研究领域

主要从事生物材料的研究,包括组织修复与再生材料、纳米生物材料、可注射生物材料、药物/生物活性因子控释等。

奖励与荣誉

科研成果在国内外杂志发表论文250余篇,其中SCI收录论文160余篇。申请发明专利50项,已获授权发明专利33项,包括美国授权专利3项。先后获得2003年度国家科技进步二等奖(第一完成人)、2014年度国家自然科学奖二等奖(第一完成人)等国家及省部级奖励7项。

1996年入选上海市科技启明星;1998年获世界华人发明博览会金奖;1999年入选上海市科技启明星跟踪计划;2000年入选教育部跨世纪优秀人才;2001年获上海市优秀科技启明星;2004年获得国家杰出青年科学基金,第二届上海市青年科技英才;2006年入选“新世纪百千万人才工程”国家级人选,获国务院特殊津贴,中国发明创业奖;2007年获上海市十大科技精英,中国青年科技奖,何梁何利基金科技创新奖;2010年获全国优秀科技工作者;2012年获上海市青年科技杰出贡献奖,国际生物材料科学与工程Fellow终身荣誉称号(International Fellow of Biomaterials Science and Engineering)。

学术成果

1. Jinyang Li, Xue Qu, Gregory F. Payne, Cheng Zhang, Yuxin Zhang, Jianbo Li, Jie Ren, Hua Hong, Changsheng Liu, Biospecific Self-Assembly of a Nanoparticle Coating for Targeted and Stimuli-Responsive Drug Delivery, Adv. Funct. Mater. 2015, DOI: 10.1002/adfm.201403636
2. Lingyan Cao, Jing Wang, Juan Hou, Wanli Xing, Changsheng Liu, Vascularization and bone regeneration in a critical sized defect using 2-N,6-O-sulfated chitosan nanoparticles incorporating BMP-2, Biomaterials, 2014, 35(2):684-698
3. Lingyan Cao, Jerome A. Werkmeister, Jing Wang, Veronica Glattauer, Keith M. McLean*, Changsheng Liu*, Bone regeneration using photocrosslinked hydrogel incorporating rhBMP-2 loaded 2-N, 6-O-sulfated chitosan nanoparticles, Biomaterials, 2014,35(9): 2730-2742
4. Fan Yang, Jing Wang, Juan Hou, Han Guo, Changsheng Liu, Bone regeneration using cell-mediated responsive degradable PEG-based scaffolds incorporating with rhBMP-2, Biomaterials, 2013, 34: 1514-1528
5. Jing Zhang, Huanjun Zhou, Kai Yang, Yuan Yuan*, Changsheng Liu*, RhBMP-2-loaded calcium silicate/calcium phosphate cement scaffold with hierarchically porous structure for enhanced bone tissue regeneration, Biomaterials, 2013, 34: 9381-9392
6. Jun Zhao, Gang Shen, Changsheng Liu, Shaoyi Wang, Wenjie Zhang, Xiaochen Zhang, Xiuli Zhang, Dongxia Ye, Jie Wei, Zhiyuan Zhang, Xinquan Jiang, Enhanced Healing of Rat Calvarial Defects with Sulfated Chitosan-Coated Calcium-Deficient Hydroxyapatite/Bone Morphogenetic Protein 2 Scaffolds, Tissue Engineering Part A, 2012, 18(1-2): 185-197
7. Deliang Zeng, Lunguo Xia, Wenjie Zhang, Hui Huang, Bin Wei, Qingfeng Huang, Jie Wei, Changsheng Liu, Xinquan Jiang, Maxillary Sinus Floor Elevation Using a Tissue-Engineered Bone with Calcium-Magnesium Phosphate Cement and Bone Marrow Stromal Cells in Rabbits, Tissue Engineering Part A, 2012, 18(7-8): 870-882
8. Derong Zou, Lian Guo, Jiayu Lu, Xiuli Zhang, Jie Wei, Changsheng Liu, Zhiyuan Zhang, Xinquan Jiang, Engineering of Bone Using Porous Calcium Phosphate Cement and Bone Marrow Stromal Cells for Maxillary Sinus Augmentation with Simultaneous Implant Placement in Goats, Tissue Engineering Part A, 2012, 18(13-14): 1464-1478
9. Chenglong Dai, Han Guo, Jingxiong Lu, Jianlin Shi, Jie Wei, Changsheng Liu*, Osteogenic evaluation of calcium/magnesium-doped mesoporous silica scaffold with incorporation of rhBMP-2 by synchrotron radiation-based mCT, Biomaterials, 2011, 32: 8506-8517
10. Wenjie Dong , Yongsheng Li*, Dechao Niu , Zhi Ma , Jinlou Gu , Yi Chen , Wenru Zhao ,Xiaohang Liu , Changsheng Liu , and Jianlin Shi*, Facile Synthesis of Monodisperse Superparamagnetic Fe3O4 Core@hybrid@Au Shell Nanocomposite for Bimodal Imaging and Photothermal Therapy, Adv. Mater. 2011, 23, 5392–5397
11. Qi Gan, Xunyu Lu, Yuan Yuan, Jiangchao Qian, Huanjun Zhou, Xun Lu, Jianlin Shi, Changsheng Liu*, A magnetic, reversible pH-responsive nanogated ensemble based on Fe3O4 nanoparticles-capped mesoporous silica, Biomaterials, 2011, 32: 1932-1942.
12. Yuan Yuan, Changsheng Liu*, Jiangchao Qian, Jing Wang, Yuan Zhang, Size-mediated cytotoxicity and apoptosis of hydroxyapatite nanoparticles in human hepatoma HepG2 cells, Biomaterials, 2010, 31:730-740.
13. Jie Wei, Junfeng Jia, FanWu, Shicheng Wei, Huanjun Zhou, Hongbo Zhang, Jung-Woog Shin, Changsheng Liu*, Hierarchically microporous/macroporous scaffold of magnesium–calcium phosphate for bone tissue regeneration, Biomaterials, 2010, 31:1260-1269.
14. Chenglong Dai, Changsheng Liu*, Jie Wei, Hua Hong, Qinghui Zhao, Molecular imprinted macroporous chitosan coated mesoporous silica xerogels for hemorrhage control, Biomaterials, 2010, 31:7620-7630.

15. Yan Sheng, Changsheng Liu*, Yuan Yuan, Xinyi Tao, Fan Yang, Xiaoqian Shan, Huanjun Zhou, Feng Xu,Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan. Biomaterials, 2009, 30: 2340-2348.